Drug | %LDL reduction | %HDL increase | %TG reduction | Side Effects (monitoring & contraindications) |
statin | 18-55 | 5-15 | 7-30 | myopathy, increased LFT |
sequestrant | 15-30 | 3-5 | nil - increase | GI, constipation, decreased drug absorption |
Niacin | 5-25 | 15-35 | 20-50 | flushing, hyperglc, gout, LFT, UGI |
fibric acid | 5-20 | 10-20 | 20-50 | dyspepsia, gallstones, myopathy, (LFT, Cr) |